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Purpose : Excessive amounts of glutamate are released into the extracelluar space during
hypoxia/ischemia and contribute to neuronal injury through overactivation of the NMDA receptors.
It will be expected that the changes of the NMDA receptors to decrease the injury are developed
as a kind of defense mechanism. The NMDA receptors are composed of NR1 and NR2, and
there are four NR2 subunits; NR2A,... |